So, not an oversight, but what is the IP patent coverage now. This Nature map is the IP landscape now – No place for them in Nature‘s display of mRNA intellectual inter-dependence! Arbutus? Moderna? Arcturus? These are typefaces, not drug companies! (Image source: Nature)Īll of the patents I am on ARE NOW ALL EXPIRED. In the absence of crucial details for implementing that concept (like stabilising the mRNA molecules and tailoring them to look less virus-like to one’s immune defenses), the patents held little value, and duly expired in 2006. His name appeared next to Felgner and others as one inventor on Vical patents US-7250404-B2 and US6867195B1 ( inter alia) on therapeutic applications of injectable mRNA, including its use as a vaccine: instructions for cells in the recipient’s body to assemble a protein, to elicit an immune response (rather than injecting the protein directly). I come here not to bury these accomplishments, but to praise them. Not disputing that Malone co-authored a 1989 paper on mRNA vaccines, but I would like to hear Verma's and Felgner's opinions before accepting that Malone was THE inventor, or THE discoverer of RNA transfection.- Smut Clyde, X-Ray Haruspex June 14, 2021Īt one stage Malone and Glasspool worked on injecting DNA as a vaccine (to be absorbed by recipient cells, expressed as mRNA, and then transcribed as protein)… which is why he described himself in 2019 on his promotional website, with unusual modesty, as “ one of the inventors of DNA vaccination”. Malone was also a minor author of a second paper from 1990, from Felgner’s Vical start-up ( “Direct Gene Transfer into Mouse Muscle in Vivo”). In biology authorship etiquette, that is the totem-pole position for the student who did the experiments, under the direction of the laboratory leader who assigned the topic and becomes the last author The Salk work produced a 1989 paper on RNA transfection with Malone as first author ( “Cationic liposome-mediated RNA transfection”). As a grad student, Malone had indeed joined a research team at the Salk Institute that had studied RNA expression / transcription, before falling out with his supervisor and moving to a start-up rather than wait around for a PhD. When Malone’s name first popped up in the churning hybrid of Ouroboros and the Human Centipede that constitutes antivax discourse, I took myself to the journals and found the same references that everyone else finds. All that matters here is that the removal of Dr Glasspool’s spamming additions gave Malone the chance to seek out the company of sympathetic medscammers and wrap himself in the mantle of a persecuted victim of a Censorship Conspiracy, just like them. ‘Orac’ at Respectful Insolence ventured into the morass, to a depth that is exhaustive even by my standards. My wife has tried to change it – but they banned her from editing (she is a multi-year editor).- Robert W Malone, MD June 16, 2021 Yep- they edit out anything with my name and also the proof of principle mRNA vaccine experiments with a priority date of 1989. Jill Glasspool Malone, Robert’s wife and for already 20 years “ President at RW Malone MD, LLC“. After Glasspool1 was blocked and her revisions were reverted, another sockpuppet ‘ Asailum‘ sprang up in her place to denounce the persecution, to defend antivax misinformation, and to blame everything on AntiFa / BLM agitators Wikipedia’s left-wing bias. Notably, Malone sockpuppet ‘ Glasspool1‘ spent March and June 2021 rewriting the entries on ‘DNA vaccine’, ‘mRNA vaccine’ and ‘RNA therapeutics’ to position Malone at the forefront of innovation. One’s first impulse is to check what Wikipedia has to say on the matter, but the otherwise-pristine waters of that fount of knowledge are muddied by the inevitable Drama. “This is not going to end well,” Malone’s message says.” “Karikó shared with me an email that Malone sent her in June, accusing her of feeding reporters bogus information and inflating her own accomplishments. The Atlantic article documents Malone’s harassment of Karikó. It seems that this paternity claim only occurred to him when Katalin Karikó and her colleagues developed the BioNTech / Pfizer mRNA vaccine against COVID-19 and licensed the same methods to Moderna, confounding the skeptics (including myself ) who’d doubted that this new technology – previously only applied to cattle – would work against a respiratory virus.
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